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Elise Clifton-Ward and Alexander Pearce/Frank Tupelo -

In 2010 we could see Angelina Jolie and Johnny Depp co-starring in 'The Tourist.' The unlikely "Deppelina" on-screen couple just weren't really into each other in real life, and we can see that in their lack of chemistry in the movie. 

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Anakin Skywalker and Padmé Amidala -

The couple played by Natalie Portman and Hayden Christensen in 'Star Wars: Episode II - Attack of the Clones' (2002) is like a pair of mismatched socks. 

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Harry Potter and Ginny Weasley -

Daniel Radcliffe and Bonnie Wright first get together as a couple in 'Harry Potter and the Half-Blood Prince' (2009). Only a magic spell would put some chemistry between these two. 

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Dave and Ronnie -

Vince Vaughn and Malin Akerman played a troubled couple in 'Couples Retreat' (2009), so the lack of chemistry was probably intentional for the roles. 

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Jay Gatsby and Daisy Buchanan -

Carey Mulligan and Leonardo DiCaprio looked cute in 'The Great Gatsby' (2013), but she's no Kate Winslet. 

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Benjamin Button and Daisy Fuller -

Brad Pitt and Cate Blanchett play this couple in 'The Curious Case of Benjamin Button' (2008). The whole romance has been called plain awkward. 

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Sabrina Peterson and Peter Brackett -

Julia Roberts and Nick Nolte play this couple in 'I Love Trouble' (1994). Apparently, the actors didn't really get along in real life, and that tension transpires in their performance. 

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Seth and Jules -

Things turned out fine between Jonah Hill and Emma Stone in 'Maniac' (2018), but we can't say the same about their chemistry in 'Superbad' (2007).

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David Aames and Julianna "Julie" Gianni -

Although things got better in 'Knight and Day' (2010), Tom Cruise and Cameron Diaz had very little chemistry in 'Vanilla Sky' (2001). 

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Hal Larson and Rosemary "Rosie" Shanahan -

There's just something off about Jack Black and Gwyneth Paltrow's characters in 'Shallow Hal' (2000).

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Superman and Lois Lane -

Henry Cavill and Amy Adams are miles away from Christopher Reeve and Margot Kidder when it comes to on-screen chemistry, and that shows in both 'Man of Steel' (2013) and 'Justice League' (2017).

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Sarah Lewis and Ben Holmes -

Name one actress with a good chemistry with Ben Affleck. That's debatable, but Sandra Bullock is probably not the one you're thinking about. They co-starred in 'Forces of Nature' (1999).

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Kate and Brad -

What an odd couple Reese Witherspoon and Vince Vaughn make in 'Four Christmases' (2008). The actors reportedly didn't get along very well either. 

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Lenny Feder and Roxanne Chase-Feder -

Of all of Adam Sandler's love interests in his rom-coms, Salma Hayek is among the worst. They just don't work well as a couple in 'Grown-Ups' (2010) and 'Grown Ups 2' (2013). 

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Longfellow Deeds and Babe Bennett -

And Winona Ryder comes next as one of Adam Sandler's most uncomfortable leading ladies, for her role in 'Mr. Deeds' (2002).

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Bruce Wayne/Batman and Rachel Dawes -

Katie Holmes and Christian Bale are yet another on-screen couple who doesn't seem to belong together. They co-star in 'Batman Begins' (2005).

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Andrea "Andy" Sachs and Nate Cooper -

Anne Hathaway and Adrian Grenier play this couple in 'The Devil Wears Prada' (2006), but it's a couple that no viewer ships. 

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Katniss Everdeen and Peeta Mellark -

Jennifer Lawrence and Josh Hutcherson make an odd couple in 'The Hunger Games' (2012). Some say they look more like siblings than lovers. 

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Abigail "Abby" Richter and Mike Chadway -

Katherine Heigl and Gerard Butler don't make a great couple. Just watch 'The Ugly Truth' (2009) if you don't believe us. 

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Josh and Cornelia Srebnick -

Ben Stiller has had many love interests in movies, but it's safe to say that Naomi Watts in 'While We're Young' (2014) was the least believable match. 

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Belle and Beast -

'Beauty and the Beast' (2017) is a beautiful story, but less beautiful is the on-screen chemistry between Emma Watson and Dan Stevens.

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Johnny and Lisa -

Tommy Wiseau and Juliette Danielle play this odd couple in 'The Room' (2003).

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Anastasia "Ana" Steele and Christian Grey -

What was supposed to be a steamy relationship between the characters played by Dakota Johnson and Jamie Dornan in the 'Fifty Shades' franchise, turned out to be a lot cheesier, and even silly at times.

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Lady Sarah Ashley and Drover -

Nicole Kidman and Hugh Jackman are not quite the great couple we'd like them to be in 'Australia' (2008).

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Bella Swan and Edward Cullen -

Our favorite teen vampires in the 'Twilight' saga, played by Kristen Stewart and Robert Pattinson, even dated in real life, but that still didn't change the fact that they had zero chemistry on the big screen.

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Barney Stinson and Robin Scherbatsky -

Played by Neil Patrick Harris and Cobie Smulders, this is likely the couple with the least chemistry in 'How I Met Your Mother.'

Sources: (IMDb) (Zimbio) (Screen Rant) (Hollywood.com) 

See also: The most essential rom-coms of the '90s

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