On-screen friends who became inseparable in real life

The two bonded immediately and became very close friends. "What a relief we’re not Hollywood friends. I just said to him an hour ago, 'Thank God we really do like each other' [...] All these people that come into our lives; my husband, my children, his wife [Amal Clooney]. We just keep stitching our lives closer together," said the actress.

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Drew Barrymore and Adam Sandler -

Who can forget the two in rom-coms such as 'The Wedding Singer' (1998) and '50 First Dates' (2004)? Off screen they became very close friends.

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Drew Barrymore and Adam Sandler -

Barrymore's book 'Wildflower' even has a chapter dedicated to the actor. It's called 'ADAM.'

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Jennifer Aniston and Courteney Cox -

Rachel Green and Monica Gellar from 'Friends' also became BFFs in real life.

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Jennifer Aniston and Courteney Cox -

"There's absolutely no judgment in Court. You'll never feel scolded. She's extremely fair, ridiculously loyal and fiercely loving," said Aniston about her bestie.

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Dwayne Johnson and Kevin Hart -

The actors became friends when they first co-starred in 'Central Intelligence' in 2016.

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Dwayne Johnson and Kevin Hart -

"It's a real friendship, it was one that I didn't anticipate, especially as you kind of get older in life, it's not like in high school or college where you just have a lot of best friends. No, he has become truly a great, great friend," said The Rock on 'Jimmy Kimmel Live!'.

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Owen Wilson and Ben Stiller -

The dynamic duo have a long list of movies together, though their first one was 'The Cable Guy' (1996).

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Owen Wilson and Ben Stiller -

The two remain close friends to this day. "From when we first became friends, walking around New York, I think that we are still sort of laughing at the same things and our dynamic is still pretty similar," said Wilson.

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Drew Barrymore and Cameron Diaz -

The actresses had met many years ago, but didn't become really close until they co-starred in 'Charlie's Angels' (2000).

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Drew Barrymore and Cameron Diaz -

"We're like more than best friends, she's my sister. We have much more of that kind of relationship; we're very honest with each other. We push each other. And we've had the majority of our lives spent side by side, really going through what real life is, which is an everyday high and low, and we just have each other's backs," said Barrymore.

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Leonardo DiCaprio and Kate Winslet -

Who can forget Jack and Rose in 'Titanic' (1997)? Okay, they were more than just friends on screen, but their friendship is really solid to this day in real life.

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Leonardo DiCaprio and Kate Winslet -

"Leo, I'm so happy I can stand here and tell you how much I love you and how much I’ve loved you for 13 years," the actress said in her Golden Globe acceptance speech in 2009.

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Ryan Reynolds and Hugh Jackman -

The actors have been inseperable ever since they met while shooting 'X-Men Origins: Wolverine' in 2009. They famously clown around a lot!

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Ryan Reynolds and Hugh Jackman -

"Despite what I tell anyone who'll listen, Hugh Jackman is one of the finest, kindest, hardest working, generous and most talented people I've had the privilege to call my friend," said Reynolds.

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Donald Faison and Zach Braff -

JD and Turk from 'Scrubs' are also good friends in real life. The two live just a few streets from each other in LA, and even have a podcast together called 'Fake Doctors, Real Friends with Zach and Donald.'

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Donald Faison and Zach Braff -

"I'm very comfortable with Zach; he's very comfortable with me. I tell him things I wouldn't tell my wife," Faison said.

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Joseph Gordon-Levitt and Zooey Deschanel -

You probably remember the duo in '500 Days of Summer' (2009), but the actors met previously, while co-starring in 2001's 'Manic.'

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Joseph Gordon-Levitt and Zooey Deschanel -

"We've been friends for 10 years. She [Zooey] loves movies, music and art, and she's incredibly knowledgeable about that stuff. It's fun just to have conversations, watch movies with her," said Gordon-Levitt.

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Lily Tomlin and Jane Fonda -

The actresses starred in the comedy '9 to 5,' back in 1980. "We've been friends ever since," said Tomlin. The duo also play best friends on the show 'Grace and Frankie.'

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Lily Tomlin and Jane Fonda -

"We're friends because I just love her. I know Jane has my back whenever she can," added Tomlin.

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Matt Damon and Ben Affleck -

Matt Damon and Ben Affleck's friendship goes back a long time. Childhood, actually. They famously got their first Oscar together for 'Good Will Hunting' (1997).

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Matt Damon and Ben Affleck -

Matt Damon opened up about how his friend was always there for him. "I certainly wouldn't be here if not for Ben Affleck."

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Tina Fey and Amy Poehler -

Their friendship dates back to 1993, when they met at an improv theater in Chicago. The duo were a hit on 'Saturday Night Live' together, then starred in numerous movies, from 'Mean Girls' in 2004 to 'Wine Country' in 2019, among others.

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Tina Fey and Amy Poehler - They are so close that Poehler dedicated a whole chapter of her book 'Yes, Please' to her bestie, calling her "the fiercest and most talented voice in the comedy world."

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Michelle Williams and Busy Philipps -

The teens from 'Dawson's Creek' really bonded in real life. So much so that they became known for attending the Oscars ceremony together in 2006, 2011, 2012, and 2017.

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Michelle Williams and Busy Philipps -

"I'm so in love with her. She's proof that the love of your life does not have to be a man! That's the love of my life right there," said Williams.

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Blake Lively, Alexis Bledel, Amber Tamblyn and America Ferrera -

Who would have thought that the cast of 'The Sisterhood of the Traveling Pants' (2005) would become so close in real life? Ever since then, the actresses have been keeping their friendship strong.

33 / 42 Fotos

Steve Martin and Martin Short -

The comedy actors first co-starred together in the 1986 movie 'Three Amigos.' They have been close friends ever since, even vacationing together with their families.

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Melissa McCarthy and Octavia Spencer -

The duo's friendship also goes back many years. Spencer even caught the bouquet at McCarthy's wedding! The actresses recently co-starred in 'Thunder Force' (2021).

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Ed Westwick and Chace Crawford -

The 'Gossip Girl' actors just happen to have great chemistry, both on and off screen. They even shared an apartment while filming in New York City.

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Maisie Williams and Sophie Turner -

Unlike the sisters they played in 'Game of Thrones,' the actresses are really close in real life.

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Maisie Williams and Sophie Turner -

"Maisie and I have the purest form of true, true friendship. We are kind of the only two people who know what it feels like to go through this very scenario from pretty much the same background, and ending up where we are and kind of finding ourselves as we go. I think that's why people respond so well to our friendship, I guess. They see the true, pure love between us," said Turner.

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Shailene Woodley and Miles Teller -

The two first met when they shot 'The Spectacular Now' in 2013, and have been friends ever since. "He helps me, I think, have more fun when I get caught up in being serious. And I think I help ground himself in a way that's perhaps more natural than his other choices," said the actress.

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Ashley Benson and Shay Mitchell -

'Pretty Little Liars' brought them together on screen, but the actresses clicked in real life too. According to Mitchell, it was "love at first sight."

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Rose Leslie and Emilia Clarke -

The actresses might not have been besties on 'Game of Thrones,' but Leslie and Clarke are really close in real life.

Sources: (Nicki Swift) (Elle) (BuzzFeed)

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Bryan Cranston and Aaron Paul -

The 'Breaking Bad' co-stars have formed an amazing bond through filming the show. Walter White and Jesse Pinkman really became friends in real life.

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Bryan Cranston and Aaron Paul -

"The storylines gave us opportunities to bond. And I was attracted to his character as a human being, which is really sound and remarkable. He's a really good person," said Cranston.

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Salma Hayek and Penélope Cruz -

The actresses have known each other since 2001. Then in 2006 they co-starred in the film 'Bandidas.' They even had a nickname for each other: "huevos" (eggs in English).

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Salma Hayek and Penélope Cruz -

"It was because when we were working together, we didn't have children yet, so we used to sleep much more than now. So it was a way to call each other lazy," explained Cruz.

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George Clooney and Julia Roberts -

Despite being Hollywood heavyweights, it wasn't until Clooney and Roberts co-starred in 2001's 'Oceans 11' that the two stars met.

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George Clooney and Julia Roberts -

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Drew Barrymore and Adam Sandler -

Who can forget the two in rom-coms such as 'The Wedding Singer' (1998) and '50 First Dates' (2004)? Off screen they became very close friends.

Getty Images

7 / 42 Fotos

Drew Barrymore and Adam Sandler -

Barrymore's book 'Wildflower' even has a chapter dedicated to the actor. It's called 'ADAM.'

Getty Images

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Jennifer Aniston and Courteney Cox -

Rachel Green and Monica Gellar from 'Friends' also became BFFs in real life.

Getty Images

9 / 42 Fotos

Jennifer Aniston and Courteney Cox -

"There's absolutely no judgment in Court. You'll never feel scolded. She's extremely fair, ridiculously loyal and fiercely loving," said Aniston about her bestie.

Getty Images

10 / 42 Fotos

Dwayne Johnson and Kevin Hart -

The actors became friends when they first co-starred in 'Central Intelligence' in 2016.

Getty Images

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Dwayne Johnson and Kevin Hart -

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Owen Wilson and Ben Stiller -

The dynamic duo have a long list of movies together, though their first one was 'The Cable Guy' (1996).

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Owen Wilson and Ben Stiller -

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Drew Barrymore and Cameron Diaz -

The actresses had met many years ago, but didn't become really close until they co-starred in 'Charlie's Angels' (2000).

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Drew Barrymore and Cameron Diaz -

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Leonardo DiCaprio and Kate Winslet -

Who can forget Jack and Rose in 'Titanic' (1997)? Okay, they were more than just friends on screen, but their friendship is really solid to this day in real life.

Getty Images

17 / 42 Fotos

Leonardo DiCaprio and Kate Winslet -

"Leo, I'm so happy I can stand here and tell you how much I love you and how much I’ve loved you for 13 years," the actress said in her Golden Globe acceptance speech in 2009.

Getty Images

18 / 42 Fotos

Ryan Reynolds and Hugh Jackman -

The actors have been inseperable ever since they met while shooting 'X-Men Origins: Wolverine' in 2009. They famously clown around a lot!

Getty Images

19 / 42 Fotos

Ryan Reynolds and Hugh Jackman -

"Despite what I tell anyone who'll listen, Hugh Jackman is one of the finest, kindest, hardest working, generous and most talented people I've had the privilege to call my friend," said Reynolds.

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Donald Faison and Zach Braff -

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Donald Faison and Zach Braff -

"I'm very comfortable with Zach; he's very comfortable with me. I tell him things I wouldn't tell my wife," Faison said.

Getty Images

22 / 42 Fotos

Joseph Gordon-Levitt and Zooey Deschanel -

You probably remember the duo in '500 Days of Summer' (2009), but the actors met previously, while co-starring in 2001's 'Manic.'

Getty Images

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Joseph Gordon-Levitt and Zooey Deschanel -

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Lily Tomlin and Jane Fonda -

The actresses starred in the comedy '9 to 5,' back in 1980. "We've been friends ever since," said Tomlin. The duo also play best friends on the show 'Grace and Frankie.'

Getty Images

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Lily Tomlin and Jane Fonda -

"We're friends because I just love her. I know Jane has my back whenever she can," added Tomlin.

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26 / 42 Fotos

Matt Damon and Ben Affleck -

Matt Damon and Ben Affleck's friendship goes back a long time. Childhood, actually. They famously got their first Oscar together for 'Good Will Hunting' (1997).

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27 / 42 Fotos

Matt Damon and Ben Affleck -

Matt Damon opened up about how his friend was always there for him. "I certainly wouldn't be here if not for Ben Affleck."

Getty Images

28 / 42 Fotos

Tina Fey and Amy Poehler -

Getty Images

29 / 42 Fotos

Tina Fey and Amy Poehler - They are so close that Poehler dedicated a whole chapter of her book 'Yes, Please' to her bestie, calling her "the fiercest and most talented voice in the comedy world."

30 / 42 Fotos

Michelle Williams and Busy Philipps -

The teens from 'Dawson's Creek' really bonded in real life. So much so that they became known for attending the Oscars ceremony together in 2006, 2011, 2012, and 2017.

Getty Images

31 / 42 Fotos

Michelle Williams and Busy Philipps -

"I'm so in love with her. She's proof that the love of your life does not have to be a man! That's the love of my life right there," said Williams.

Getty Images

32 / 42 Fotos

Blake Lively, Alexis Bledel, Amber Tamblyn and America Ferrera -

Who would have thought that the cast of 'The Sisterhood of the Traveling Pants' (2005) would become so close in real life? Ever since then, the actresses have been keeping their friendship strong.

Getty Images

33 / 42 Fotos

Steve Martin and Martin Short -

The comedy actors first co-starred together in the 1986 movie 'Three Amigos.' They have been close friends ever since, even vacationing together with their families.

Getty Images

34 / 42 Fotos

Melissa McCarthy and Octavia Spencer -

The duo's friendship also goes back many years. Spencer even caught the bouquet at McCarthy's wedding! The actresses recently co-starred in 'Thunder Force' (2021).

Getty Images

35 / 42 Fotos

Ed Westwick and Chace Crawford -

The 'Gossip Girl' actors just happen to have great chemistry, both on and off screen. They even shared an apartment while filming in New York City.

Getty Images

36 / 42 Fotos

Maisie Williams and Sophie Turner -

Unlike the sisters they played in 'Game of Thrones,' the actresses are really close in real life.

Getty Images

37 / 42 Fotos

Maisie Williams and Sophie Turner -

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38 / 42 Fotos

Shailene Woodley and Miles Teller -

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Ashley Benson and Shay Mitchell -

'Pretty Little Liars' brought them together on screen, but the actresses clicked in real life too. According to Mitchell, it was "love at first sight."

Getty Images

40 / 42 Fotos

Rose Leslie and Emilia Clarke -

The actresses might not have been besties on 'Game of Thrones,' but Leslie and Clarke are really close in real life.

Sources: (Nicki Swift) (Elle) (BuzzFeed)

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On-screen friends who became inseparable in real life

BFFs in real life

30/07/24 | StarsInsider

CELEBRITY International friendship day

Friendships should be cherished, and some actors were fortunate enough to find great friends while working. The actors and actresses in this gallery built incredible bonds with their fellow co-stars. They did so while playing friends in a movie or TV show and have become inseparable ever since.

Click through and get to know the on-screen friends who became BFFs in real life!